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NEJM Genetics 新英格兰-遗传学
Aquaporin-1 Expression and Ultrafiltration of the Peritoneal Membrane
Peritoneal dialysis in adults involves diffusion and osmosis through a peritoneal membrane, measuring 1 m2, that is highly...
AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis
Abstract Background Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure w...
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion
Abstract Background Structural birth defects occur in approximately 3% of live births; most such defects lack defined gene...
Optogenetics — The Might of Light
Optogenetics Recognized through the Lasker Award This year’s Lasker Basic Medical Research Award goes to Drs. Deisseroth, ...
In Gratitude for mRNA Vaccines
mRNA Vaccine Research and the Lasker–DeBakey Award Although the production time (11 months) of the messenger RNA vaccines ...
Race, Genetic Ancestry, and Estimating Kidney Function in CKD
Abstract Background The inclusion of race in equations to estimate the glomerular filtration rate (GFR) has become controv...
Breast Cancer, HER2 Mutations, and Overcoming Drug Resistance
HER2-Mutated Breast Cancer and Resistance to TKI A recent study suggests that HER2-mutated breast cancer may develop resis...
Somatic PIK3CA Mutations in Sporadic Cerebral Cavernous Malformations
Abstract Background Cerebral cavernous malformations (CCMs) are common sporadic and inherited vascular malformations of th...
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